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1

Reactions of the antitumor agent carminic acid and derivatives with DNA

J.William Lown, Hsiao-Hsiung Chen, Soo-Khoon Sim, James A. Plambeck

Journal:

Bioorganic Chemistry

Year:

1979

Language:

english

File:

PDF, 482 KB

english, 1979

2

A facile synthesis of staurosporine aglycone

Guojian Xie, J. William Lown

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 247 KB

english, 1994

3

Active patient involvement in the education of health professionals

Angela Towle, Lesley Bainbridge, William Godolphin, Arlene Katz, Cathy Kline, Beth Lown, Ioana Madularu, Patricia Solomon, Jill Thistlethwaite

Journal:

Medical Education

Year:

2010

Language:

english

File:

PDF, 113 KB

english, 2010

4

FTIR Study of Specific Binding Interactions Between DNA Minor Groove Binding Ligands and Polynucleotides

Adnet, F., Liquier, J., Taillandier, E., Singh, Malvinder P., Rao, K. Ekambareswara, Lown, J. William

Journal:

Journal of Biomolecular Structure and Dynamics

Year:

1992

Language:

english

File:

PDF, 543 KB

english, 1992

5

An Appeal for Nuclear Sanity

Lown, Bernard, Chazov, Eugene I., Foege, William H., Ul-Majeed, Saeed, Reddy, R. Jayachandra

Journal:

JAMA The Journal of the American Medical Association

Year:

1998

Language:

english

File:

PDF, 83 KB

english, 1998

6

Intimate Partner Violence and Health: Self-Assessed Health, Chronic Health, and Somatic Symptoms Among Mexican American Women

Lown, E. Anne, Vega, William A.

Journal:

Psychosomatic Medicine

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

7

Polyazamacrocycles. V. Structure of Isomeric 3,5,7,7,10,12,14,14-Octamethyl-1,4,8,11-tetraazacyclotetradecanes

Bembi, Ramesh, M. Sondhi, Sham, K. Singh, Ashok, K. Jhanji, Amrit, G. Roy, Tapashi, Lown, J. William, Ball, R. G.

Journal:

Bulletin of the Chemical Society of Japan

Year:

1989

File:

PDF, 761 KB

1989

8

Structural Characterization of Side-by-Side Binding for a Cross-Linked Lexitropsin Dimer Designed to Target G · C Base Pairs in the DNA Minor Groove

Malvinder P. Singh, William A. Wylie, J. William Lown

Journal:

Magnetic Resonance in Chemistry

Year:

1996

Language:

english

File:

PDF, 1.14 MB

english, 1996

9

Immunophotodynamic therapy: Current developments and future prospects

Gerald G. Miller, J. William Lown

Journal:

Drug Development Research

Year:

1997

Language:

english

File:

PDF, 453 KB

english, 1997

10

Synthesis of Geometrically Constrained Unsymmetrical Bis(polyamides) Related to the Antiviral Distamycin

Sanjay K. Sharma, Manju Tandon, J. William Lown

Journal:

European Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 331 KB

english, 2000

11

Characterization of the reaction products of deoxyguanosine with the anticancer agent BFNU and BFNU-1,1,1′, 1′ -d4 in different buffers by high-performance liquid chromatography/atmospheric pressure ionization tandem mass spectrometry

Michael G. Ikonomou, Ali Naghipur, J. William Lown, Paul Kebarle

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1990

Language:

english

File:

PDF, 1.26 MB

english, 1990

12

ChemInform Abstract: Pyrroloquinoline and Pyridoacridine Alkaloids from Marine Sources

Qizhu Ding, Kelly Chichak, J. William Lown

Journal:

Year:

1999

File:

PDF, 24 KB

1999

13

ChemInform Abstract: Synthesis of an Unsymmetrical Bis-lexitropsin-1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI) Conjugate.

Guofeng Jia, Hirokazu Iida, J. William Lown

Journal:

Year:

1999

File:

PDF, 31 KB

1999

14

ChemInform Abstract: Design and Synthesis of Novel Pyrrolo[2,1-c][1,4]benzodiazepine — Lexitropsin Conjugates.

Yalamati Damayanthi, B. S. Praveen Reddy, J. William Lown

Journal:

Year:

1999

File:

PDF, 24 KB

1999

15

ChemInform Abstract: Design and Synthesis of Cyclopropylpyrroloindole (CPI)— Lexitropsin Conjugates and Related Structures

Hirokazu Iida, J. William Lown

Journal:

Year:

2000

File:

PDF, 25 KB

2000

16

ChemInform Abstract: Design and Synthesis of Novel Thiazole-Containing Cross-Linked Polyamides Related to the Antiviral Antibiotic Distamycin.

Sanjay K. Sharma, Manju Tandon, J. William Lown

Journal:

Year:

2000

File:

PDF, 28 KB

2000

17

ChemInform Abstract: Novel Cyclopropylindole Conjugates and Dimers: Synthesis and Anticancer Evaluation

Sanjay K. Sharma, Guofeng Jia, J. William Lown

Journal:

Year:

2001

File:

PDF, 25 KB

2001

18

Design, Synthesis and in vitro Cytotoxicity Studies of Novel Pyrrolo[2,1][1,4]benzodiazepine-glycosylated Pyrrole and Imidazole Polyamide Conjugates.

Rohtash Kumar, J. William Lown

Journal:

Year:

2004

File:

PDF, 52 KB

2004

19

Synthesis and Antitumor Cytotoxicity Evaluation of Novel Thiazole-Containing Glycosylated Polyamides

Rohtash Kumar, J. William Lown

Journal:

European Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 186 KB

english, 2003

20

Synthesis and NMR characterization of selectively 15N-labelled trans- and cis-butenediamido-linked bis-netropsins

Bertrand Plouvler, Malvinder P. Singh, J. William Lown

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1995

Language:

english

File:

PDF, 766 KB

english, 1995

21

Synthesis and biodistribution of 14C-radiolabelled hypocrellin B

Jixiang Liu, Gerald G. Miller, Liren Huang, Zhenjun Diwu, J. William Lown, Kevin Brown, Ronald B. Moore, John Tulip, Malcolm S. McPhee

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1995

Language:

english

File:

PDF, 395 KB

english, 1995

22

Molecular recognition between oligopeptides and nucleic acids. Specificity of binding of a monocationic bis-furan lexitropsin to DNA deduced from footprinting and 1H NMR studies

Moses Lee, Krzysztof Krowicki, Regan G. Shea, J. William Lown, Richard T. Pon

Journal:

Journal of Molecular Recognition

Year:

1989

Language:

english

File:

PDF, 969 KB

english, 1989

23

Molecular recognition between oligopeptides and nucleic acids. DNA sequence specificity and binding properties of an acridine-linked netropsin hybrid ligand

Christian Bailly, Nicole Helbecque, Jean-Pierre Hénichart, Pierre Colson, Claude Houssier, K. Ekambareswara Rao, Regan G. Shea, J. William Lown

Journal:

Journal of Molecular Recognition

Year:

1990

Language:

english

File:

PDF, 1.08 MB

english, 1990

24

DNA recognition by lexitropsins, minor groove binding agents

J. William Lown

Journal:

Journal of Molecular Recognition

Year:

1994

Language:

english

File:

PDF, 1.10 MB

english, 1994

25

Sequential assignments in deoxyribonucleotide tetramers by 31P/1H two-dimensional shift correlation NMR spectroscopy

Albin Otter, J. William Lown, George Kotovych

Journal:

Magnetic Resonance in Chemistry

Year:

1986

Language:

english

File:

PDF, 426 KB

english, 1986

26

Selective long-range 1H13C polarization transfer in nucleosides

William H. Gmeiner, J. William Lown

Journal:

Magnetic Resonance in Chemistry

Year:

1992

Language:

english

File:

PDF, 440 KB

english, 1992

27

Two-dimensional double-quantum spectroscopy for the hydrogen NMR assignment of oligodeoxyribonucleotides

Christopher C Hanstock, J.William Lown

Journal:

Journal of Magnetic Resonance (1969)

Year:

1969

Language:

english

File:

PDF, 347 KB

english, 1969

28

Conformations of the antitumor agent 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-urea in solution studied by 15N-NMR

J. William Lown, Shive M.S. Chauhan

Journal:

Tetrahedron Letters

Year:

1981

Language:

english

File:

PDF, 201 KB

english, 1981

29

Reaction of dicyanomethylides with 3-(3′,3′-dimethyltriazene-1-yl)- pyridine-4-carboxylic acid. Unexpected preferential formation of pyrido[4,3-a]indolizines

Kiyoshi Matsumoto, Takane Uchida, Mituo Toda, Kinuyo Aoyama, Akikazu Kakehi, Atsushi Shigihara, J.William Lown

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 263 KB

english, 1992

30

Reaction of 3-aroylaziridines with diphenylcyclopropenone. 1,3-Dipole cascade from azomethine ylide to carbonyl ylide

Kiyoshi Matsumoto, Yukio Ikemi, Mitsuo Toda, Akikazu Kakehi, Takane Uchida, James William Lown

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 152 KB

english, 1995

31

Reaction of 3-aroylaziridines with diphenylcyclopropenone and subsequent stereospecific 1,3-dipolar cycloaddition of the adducts with dimethyl 1-cyclobutene 1,2-dicarboxylate

Kiyoshi Matsumoto, Yukio Ikemi, Akikazu Kakehi, Atsushi Shigihara, J.William Lown

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 231 KB

english, 1995

32

Studies related to antitumor antibiotics: X. Reactions of maytansine and its analogs with DNA in vitro

J.William Lown, Krishna C. Majumdar, Albert I. Meyers, Ann Hecht

Journal:

Bioorganic Chemistry

Year:

1977

Language:

english

File:

PDF, 739 KB

english, 1977

33

Photoreaction of psoralen and other furocoumarins with nucleic acids

J.William Lown, Soo-Khoon Sim

Journal:

Bioorganic Chemistry

Year:

1978

Language:

english

File:

PDF, 731 KB

english, 1978

34

Photosensitization by selected anticancer agents

Krzysztof Reszka, John A. Hartley, J.William Lown

Journal:

Biophysical Chemistry

Year:

1990

Language:

english

File:

PDF, 1021 KB

english, 1990

35

Protein kinase C-α inhibitors; structure-activity relationships in bis-indole series

Guojian Xie, Jürg Zimmermann, Thomas Meyer, J. William Lown

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 144 KB

english, 1995

36

Design, synthesis and evaluation of novel bismustard cross-linked lexitropsins

Yong-Huang Chen, Ji-Xiang Liu, J.William Lown

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 406 KB

english, 1995

37

Novel substituted indolocarbazoles as potent and selective inhibitors of protein kinase C

Guojian Xie, Hiroyuki Nagata, Tatsuya Tamaoki, J.William Lown

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 159 KB

english, 1995

38

Synthesis and antitumor activity of camptothecin derivatives bearing five-membered heterocycle containing 10-substituents

Rulin Zhao, Bernadette Oreski, J.William Lown

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 168 KB

english, 1995

39

Synthesis and biological evaluation of hybrid molecules containing the pyrroloquinoline nucleus and DNA-minor groove binders

Rulin Zhao, Bernadette Oreski, J. William Lown

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 169 KB

english, 1996

40

Design, synthesis and sequence selective DNA cleavage of functional models of bleomycin—II. 1,2-trans-disubstituted cyclopropane units as novel linkers

Liren Huang, James C. Quada Jr, J. William Lown

Journal:

Bioorganic & Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.10 MB

english, 1995

41

Photosensitization by anticancer agents 12. Perylene quinonoid pigments, a novel type of singlet oxygen sensitizer

Zhenjun Diwu, J.William Lown

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

1992

Language:

english

File:

PDF, 1.09 MB

english, 1992

42

Photosensitization with anticancer agents 13. The production of singlet oxygen by halogenated and metal-ion-chelated perylenequinones

Shenjun Diwu, Cailan Zhang, J.William Lown

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

43

Photosensitization with anticancer agents 14. Perylenequinonoid pigments as new potential photodynamic therapeutic agents: formation of tautomeric semiquinone radicals

Zhenjun Diwu, J.William Lown

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Year:

1992

Language:

english

File:

PDF, 830 KB

english, 1992

44

Photosensitization by anticancer agents 11. Mechanisms of photosensitization of human leukemic cells by diaminoanthraquinones: Singlet oxygen and radical reactions

Krzystzof J. Reszka, P. Bilski, Colin F. Chignell, John A. Hartley, Naem Khan, Robert L. Souhami, Aubrey J. Mendonca, J.William Lown

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

1992

Language:

english

File:

PDF, 1.24 MB

english, 1992

45

Photosensitization with anticancer agents: 15. Perylenequinonoid pigments as potential photodynamic therapeutic agents: Formation of semiquinone radicals and reactive oxygen species on illumination

Zhenjun Diwu, J.William Lown

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

1993

Language:

english

File:

PDF, 1.48 MB

english, 1993

46

Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates

Rohtash Kumar, J. William Lown

Journal:

European Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 474 KB

english, 2005

47

Synthetic studies in novel hypocrellin B derivatives

Jixiang Liu, Zhenjun Diwu, J.William Lown

Journal:

Year:

1993

Language:

english

File:

PDF, 532 KB

english, 1993

48

A simple high-yielding approach to perylenequinone from the novel one-step double coupling reaction of 1,2-naphtoquinone

Zhenjun Diwu, J. William Lown

Journal:

Year:

1992

Language:

english

File:

PDF, 762 KB

english, 1992

49

Design and synthesis of new thiazolated cross-linked DNA binding polyamides for altered sequence recognition

Sanjay K Sharma, Manju Tandon, J.William Lown

Journal:

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

50

Convenient syntheses of pyrroloiminoquinone and its lexitropsin-linked derivative

Huiying Wang, Naim H. Al-Said, J.William Lown

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 157 KB

english, 1994

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